Recombinant Human Spermatogenesis-associated protein 4 (SPATA4)

Code CSB-YP850876HU
MSDS
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Source Yeast
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Code CSB-EP850876HU
MSDS
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Source E.coli
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Code CSB-EP850876HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP850876HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP850876HU
MSDS
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Source Mammalian cell
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Product Details

Purity
≥85% (SDS-PAGE)
Target Names
SPATA4
Uniprot No.
Alternative Names
SPATA4; TSARG2; Spermatogenesis-associated protein 4; Testis and spermatogenesis cell-related protein 2; Testis spermatocyte apoptosis-related gene 2 protein
Species
Homo sapiens (Human)
Expression Region
1-305
Target Protein Sequence
MAAAGQEKGY LTQTAAALDK SPSLSPQLAA PIRGRPKKCL VYPHAPKSSR LSRSVLRWLQ GLDLSFFPRN INRDFSNGFL IAEIFCIYYP WELELSSFEN GTSLKVKLDN WAQLEKFLAR KKFKLPKELI HGTIHCKAGV PEILIEEVYT LLTHREIKSI QDDFVNFTDY SYQMRLPLVS RSTVSKSIKD NIRLSELLSN PNMLTNELKA EFLILLHMLQ RKLGRKLNPE WFDVKPTVGE VTLNHLPAQA SGRRYNLKVK RGRVVPVLPN IGSGGSSHRE IHVKQAGQHS YYSAMKPIRN MDKKP
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
May play a role in apoptosis regulation.
Gene References into Functions
  1. SPATA4 protects HeLa cells against etoposide-induced apoptosis through the mitochondrial apoptotic pathway, providing further evidence that SPATA4 plays a role in regulating apoptosis PMID: 26424010
  2. Results suggest a role for SPATA4 in membrane traffic and a specialized function for TRAPP in spermatocytes. PMID: 21827752
  3. expressed in many tissues and mapped to chromosome 4q33-34.1 by database analyses PMID: 12019456
  4. TSARG2 may play an important role in the development of cryptorchid testis and be a testis-specific apoptosis candidate oncogene PMID: 15158438
  5. analysis of SPATA4 expression and variation in promotor sequences PMID: 16336790

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Subcellular Location
Nucleus.
Tissue Specificity
Highly expressed in testis, the expression is observed precisely in seminiferous tubules.
Database Links

HGNC: 17333

OMIM: 609879

KEGG: hsa:132851

STRING: 9606.ENSP00000280191

UniGene: Hs.481235

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