Recombinant Human Talanin (ZNF365)

Code CSB-YP754628HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP754628HU
MSDS
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Source E.coli
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Code CSB-EP754628HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP754628HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP754628HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
ZNF365
Uniprot No.
Alternative Names
ZNF365; KIAA0844; Talanin
Species
Homo sapiens (Human)
Expression Region
1-216
Target Protein Sequence
MSALGQITIT VSRCWNTERN QTDKNPCLHG AYLQLRETVK NKSTHLKKPL MKQAPPWKDH LTFQPLHPAE RKTQVWRWQS GNSSDLETTS SASPWPTGSN RDVVLNTLAE SCCGLSELIT APPYAGVSIQ GFSQIWVLFP FCGGTFHHNE KDVLGLQDFE RESVSTSQSR NISLLTLGQL QNCVIGKLTI IDLLTEHLLG VRHGVICFPW GLPSSS
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May play a role in uric acid excretion.
Gene References into Functions
  1. It regulates cortical cell positioning and neurite extension by sustaining the anterograde transport of Lis1/DISC1 through control of Ndel1 phosphorylation PMID: 27333658
  2. The SNP rs10995251 in ZNF365 gene is associated with the susceptibility to bronchial asthma in children. PMID: 26287344
  3. we discuss the expression of DISC1, DBZ, and SGK1 , their roles in the regulation of oligodendrocyte function, possible interactions of DISC1 and DBZ in relation to SZ, and the activation of the SGK1 signaling cascade in relation to MDD. PMID: 25705664
  4. We evaluated the association of polymorphisms of ZNF365 gene with the metabolic disorders in children with urolithiasis PMID: 25060549
  5. Single-nucleotide polymorphism in ZNF365 gene is associated with Crohn's disease. PMID: 25489960
  6. In the absence of ZNF365, defective telomeres engage in aberrant recombination of telomere ends, leading to increased telomere sister chromatid exchange and formation of anaphase DNA bridges, including ultra-fine DNA bridges, and ultimately increased cytokinesis failure and aneuploidy PMID: 23776040
  7. These results suggest an homologous recombination repair-dependent function of ZNF365 in preventing genomic instability. PMID: 23966166
  8. Our findings suggest that RAB3GAP1 and ZNF365 are relevant candidate genes for SCD and will contribute to the mechanistic understanding of SCD susceptibility. PMID: 23593153
  9. Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. PMID: 22351618
  10. the non-synonymous Ala62Thr SNP, rs7076156, underlies the association between 10q21 and CD risk and suggest that this SNP acts by altering expression of genes under the control of ZNF365 isoform D. PMID: 21257989
  11. The association of PCNT2 and DBZ with schizophrenia and bipolar disorder in a case-control study of Japanese cohorts, was examined. PMID: 19191256
  12. A novel gene responsible for UAN was identified in an Italian population. PMID: 12740763
  13. findings indicate that Su48 can form a protein complex with Nde1 in the centrosome and plays an important role for successful mitosis PMID: 16682949

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Involvement in disease
Uric acid nephrolithiasis (UAN)
Tissue Specificity
Isoform 4 is expressed in placenta, lung, kidney and pancreas.
Database Links

HGNC: 18194

OMIM: 605990

STRING: 9606.ENSP00000387091

UniGene: Hs.22653

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