Recombinant Human Teneurin-3 (ODZ3), partial

Code CSB-YP865205HU
MSDS
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Source Yeast
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Code CSB-EP865205HU
MSDS
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Source E.coli
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Code CSB-EP865205HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP865205HU
MSDS
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Source Baculovirus
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Code CSB-MP865205HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
TENM3
Uniprot No.
Alternative Names
FLJ10474; FLJ10886; KIAA1455; odd Oz Ten m homolog 3; odz odd Oz ten m homolog 3 (Drosophila); odz odd Oz ten m homolog 3; ODZ3 like protein; Protein Odd Oz ten m homolog 3; Protein Odd Oz/ten-m homolog 3; Ten 3; Ten M3; Ten-3; Ten-m3; TEN3_HUMAN; Tenascin M3; Tenascin-M3; Teneurin 3; Teneurin transmembrane protein 3; Teneurin-3; Teneurin3; tenm3; TNM3
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Involved in neural development by regulating the establishment of proper connectivity within the nervous system. Acts in both pre- and postsynaptic neurons in the hippocampus to control the assembly of a precise topographic projection: required in both CA1 and subicular neurons for the precise targeting of proximal CA1 axons to distal subiculum, probably by promoting homophilic cell adhesion. Required for proper dendrite morphogenesis and axon targeting in the vertebrate visual system, thereby playing a key role in the development of the visual pathway. Regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May also be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes.
Gene References into Functions
  1. This report supports the association of TENM3 mutations with colobomatous microphthalmia and expands the phenotypic spectrum associated with mutations in this gene PMID: 27103084
  2. Null mutation in ODZ3 causes autosomal recessive microphthalmia in humans. PMID: 22766609
Involvement in disease
Microphthalmia, isolated, with coloboma, 9 (MCOPCB9)
Subcellular Location
Cell membrane; Single-pass membrane protein. Cell projection, axon.
Protein Families
Tenascin family, Teneurin subfamily
Tissue Specificity
Expressed in adult and fetal brain, slightly lower levels in testis and ovary, and intermediate levels in all other peripheral tissues examined. Not expressed in spleen or liver. Expression was high in brain, with highest levels in amygdala and caudate nu
Database Links

HGNC: 29944

OMIM: 610083

KEGG: hsa:55714

STRING: 9606.ENSP00000385276

UniGene: Hs.130438

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