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Recombinant Human Vascular non-inflammatory molecule 3 (VNN3)

Recombinant Human Vascular non-inflammatory molecule 3 (VNN3)

Code	CSB-YP873689HU
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Yeast
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Code	CSB-EP873689HU
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
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Code	CSB-EP873689HU-B
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
Conjugate	Avi-tag Biotinylated E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code	CSB-BP873689HU
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Baculovirus
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Code	CSB-MP873689HU
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Mammalian cell
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

VNN3

Uniprot No.

Q9NY84

Alternative Names

VNN3; Vascular non-inflammatory molecule 3; Vanin-3; EC 3.5.1.92

Species

Homo sapiens (Human)

Expression Region

23-470

Target Protein Sequence

LDTFIAAV YEHAVILPNR TETPVSKEEA LLLMNKNIDV LEKAVKLAAK QGAHIIVTPE DGIYGWIFTR ESIYPYLEDI PDPGVNWIPC RDPWRFGNTP VQQRLSCLAK DNSIYVVANI GDKKPCNASD SQCPPDGRYQ YNTDVVFDSQ GKLLARYHKY NLFAPEIQFD FPKDSELVTF DTPFGKFGIF TCFDIFSHDP AVVVVDEVSI DSILYPTAWY NTLPLLSAVP FHSAWAKAMG VNLLAANTHN TSMHMTGSGI YAPEAVKVYH YDMETESGQL LLSELKSRPR REPTYPAAVD WHAYASSVKP FSSEQSDFLG MIYFDEFTFT KLKRNTGNYT ACQKDLCCHL TYKMSEKRTD EIYALGAFDG LHTVEGQYYL QICALLKCQT TDLETCGEPV GSAFTKFEDF SLSGTFGTRY VFPQIILSGS QLAPERHYEI SRDGRLRSRS

Protein Length

Full Length of Mature Protein

Tag Info

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer before Lyophilization

Tris/PBS-based buffer, 6% Trehalose.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet

Please contact us to get it.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine.

Gene References into Functions

The expression of SLC22A4, IL1R2 and VNN3, were independently associated with elevated neutrophil-to-lymphocyte ratio in chronic heart failure patients. PMID: 29901123
vanin-1 and vanin-3 are induced at the mRNA and protein level by psoriasis-associated proinflammatory cytokines (Th17/Th1) but not by Th2 cytokines. PMID: 19322213

Subcellular Location

Secreted.

Protein Families

Carbon-nitrogen hydrolase superfamily, BTD/VNN family

Tissue Specificity

Expressed in neutrophils (at protein level). Detected in liver, peripheral blood leukocytes and placenta. Expressed in differentiated keratinocytes in epidermis and in epithelial cells in dermis. Overexpressed in lesional psoriatic skin.

Database Links

HGNC: 16431

OMIM: 606592

KEGG: hsa:55350

STRING: 9606.ENSP00000440594

UniGene: Hs.183656

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