Recombinant Human X-ray radiation resistance-associated protein 1 (XRRA1)

Code CSB-YP747397HU
MSDS
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Source Yeast
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Code CSB-EP747397HU
MSDS
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Source E.coli
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Code CSB-EP747397HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP747397HU
MSDS
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Source Baculovirus
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Code CSB-MP747397HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
XRRA1
Uniprot No.
Alternative Names
XRRA1; X-ray radiation resistance-associated protein 1
Species
Homo sapiens (Human)
Expression Region
1-792
Target Protein Sequence
MAFSGIYKLD DGKPYLNNCF PARNLLRVPE EGQGHWLVVQ KGNLKKKPKG LVGAQAERRE SLKATSFEFK GKKESRRENQ VDLPGHILDQ AFLLKHHCVR KPSDLCTINA KENDFKHFHS VIYINASENL LPLEAFHTFP ALKELDLAFN GIKTIYVKYG DFKLLEFLDL SFNSLTVEAI CDLGILPHLR VLLLTGNGLT SLPPNLAVAE QEASVTSLTS KRYILRFPAL ETLMLDDNRL SNPSCFASLA GLRRLKKLSL DENRIIRIPY LQQVQLYDES VDWNGGRGSP HKEPQFMLQS KPRMLEDSDE QLDYTVLPMK KDVDRTEVVF SSYPGFSTSE TTKICSLPPI FEILPVKSLK ARNQTLAPPF PELRYLSLAY NKIAKEDAVL PVALFPSLCE FVFHNNPLVA HTRGVPPLLK SFLQERLGIH LIRRKIVKPK HHVLMSRKES WKVKSEIPKV PKQPLVLHHP RMTTTKSPSK DMLEPEAELA EDLPTTKSTS VESEMPTENL EGHSPSCRTF VPLPPICSNS TVHSEETLSH LSDTTVRLSP ERPSDEDSKS TESIFLTQVS ELPSSVIHKD DLELKEKDQK KPPTAPREVK GTRRKLPTAF LPSKYHGYEE LLTAKPDPAF IEPKGIQKNA QALQQMLKHP LLCHSSKPKL DTLQKPYVHK EKRAQRIPIP PPKKTRAQLL DDIFIRLRDP RNITEAPLGA VLHQWTERRL VNHKQYLEAK RLLKEFQARY RQLVSGSLRT VFGTTPLPMA CPALSESQPK FGHFLEFMDE FCQEPTASDS QG
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May be involved in the response of cells to X-ray radiation.
Gene References into Functions
  1. our results identify a novel link between XRRA1 and the ATM/CHK1/2 pathway and suggest that XRRA1 is involved in a DNA damage response that drives radio- and chemoresistance by regulating the ATM/CHK1/2 pathway. PMID: 29082250
  2. Molecular cloning and gene expression patterns of XRRA1. PMID: 12908878
Subcellular Location
Cytoplasm. Nucleus.
Tissue Specificity
Expressed predominantly in testis followed by prostate and ovary. Low levels found in other tissues including peripheral blood leukocytes, spleen, thymus, small intestine and colon. Also expressed in neuroblastoma, glioma, breast, lung, leukemia, renal, o
Database Links

HGNC: 18868

OMIM: 609788

KEGG: hsa:143570

STRING: 9606.ENSP00000339918

UniGene: Hs.370145

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