Recombinant Human Zinc finger protein 202 (ZNF202)

Code CSB-YP026575HU
MSDS
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Source Yeast
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Code CSB-EP026575HU
MSDS
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Source E.coli
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Code CSB-EP026575HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP026575HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP026575HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
ZNF202
Uniprot No.
Alternative Names
ZNF202; ZKSCAN10; Zinc finger protein 202; Zinc finger protein with KRAB and SCAN domains 10
Species
Homo sapiens (Human)
Expression Region
1-648
Target Protein Sequence
MATAVEPEDQ DLWEEEGILM VKLEDDFTCR PESVLQRDDP VLETSHQNFR RFRYQEAASP REALIRLREL CHQWLRPERR TKEQILELLV LEQFLTVLPG ELQSWVRGQR PESGEEAVTL VEGLQKQPRR PRRWVTVHVH GQEVLSEETV HLGVEPESPN ELQDPVQSST PEQSPEETTQ SPDLGAPAEQ RPHQEEELQT LQESEVPVPE DPDLPAERSS GDSEMVALLT ALSQGLVTFK DVAVCFSQDQ WSDLDPTQKE FYGEYVLEED CGIVVSLSFP IPRPDEISQV REEEPWVPDI QEPQETQEPE ILSFTYTGDR SKDEEECLEQ EDLSLEDIHR PVLGEPEIHQ TPDWEIVFED NPGRLNERRF GTNISQVNSF VNLRETTPVH PLLGRHHDCS VCGKSFTCNS HLVRHLRTHT GEKPYKCMEC GKSYTRSSHL ARHQKVHKMN APYKYPLNRK NLEETSPVTQ AERTPSVEKP YRCDDCGKHF RWTSDLVRHQ RTHTGEKPFF CTICGKSFSQ KSVLTTHQRI HLGGKPYLCG ECGEDFSEHR RYLAHRKTHA AEELYLCSEC GRCFTHSAAF AKHLRGHASV RPCRCNECGK SFSRRDHLVR HQRTHTGEKP FTCPTCGKSF SRGYHLIRHQ RTHSEKTS
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Transcriptional repressor that binds to elements found predominantly in genes that participate in lipid metabolism. Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipid processing (lipoprotein lipase, lecithin cholesteryl ester transferase), transporters involved in lipid homeostasis (ABCA1, ABCG1), and several genes involved in processes related to energy metabolism and vascular disease.
Gene References into Functions
  1. This is the first study to suggest that ZNF202 could be a new candidate gene for ischemic heart disease and myocardial infarction in the general population. PMID: 16289551
  2. findings show that genetic variation in ZNF202 is common in the general population. However, SNPs in the protein-coding region of ZNF202 do not make a major contribution to HDL cholesterol levels. PMID: 16467280
  3. SOX17-Chromatin immunoprecipitation identified zinc finger protein 202 (Zfp202) as a direct target of SOX17 during endoderm differentiation of F9 embryonal carcinoma cells. PMID: 18523156
  4. Homozygosity for a common functional promoter variant in ZNF202 predicts severe atherosclerosis and an increased risk of IHD. PMID: 18652945
Subcellular Location
Nucleus.
Tissue Specificity
Highly expressed in testis. Also expressed in breast carcinoma cell lines.
Database Links

HGNC: 12994

OMIM: 603430

KEGG: hsa:7753

STRING: 9606.ENSP00000337724

UniGene: Hs.112556

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