Recombinant Human mTERF domain-containing protein 3, mitochondrial (MTERFD3)

Code CSB-YP669874HU
MSDS
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Source Yeast
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Code CSB-EP669874HU
MSDS
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Source E.coli
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Code CSB-EP669874HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP669874HU
MSDS
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Source Baculovirus
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Code CSB-MP669874HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
MTERF2
Uniprot No.
Alternative Names
Hypothetical protein DKFZp667I1824 ; mitochondrial; Mitochondrial transcription termination factor 2; Mitochondrial transcription termination factor-like protein; MTER3_HUMAN; MTERF domain containing 3; mTERF domain-containing protein 3; mTERF domain-containing protein 3; mitochondrial; mTERF2; Mterfd3; mTERFL; Transcription termination factor 2 mitochondrial; Transcription termination factor like protein
Species
Homo sapiens (Human)
Expression Region
36-385
Target Protein Sequence
TTDKQ SSKENTRTVE KLYKCSVDIR KIRRLKGWVL LEDETYVEEI ANILQELGAD ETAVASILER CPEAIVCSPT AVNTQRKLWQ LVCKNEEELI KLIEQFPESF FTIKDQENQK LNVQFFQELG LKNVVISRLL TAAPNVFHNP VEKNKQMVRI LQESYLDVGG SEANMKVWLL KLLSQNPFIL LNSPTAIKET LEFLQEQGFT SFEILQLLSK LKGFLFQLCP RSIQNSISFS KNAFKCTDHD LKQLVLKCPA LLYYSVPVLE ERMQGLLREG ISIAQIRETP MVLELTPQIV QYRIRKLNSS GYRIKDGHLA NLNGSKKEFE ANFGKIQAKK VRPLFNPVAP LNVEE
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Binds mitochondrial DNA and plays a role in the regulation of transcription of mitochondrial mRNA and rRNA species.
Gene References into Functions
  1. These findings demonstrate that MTERF2 contributes to MPP(+)-induced mitochondrial disruption and cell damage. PMID: 26826381
  2. MTERFD1 and MTERFD3 have a role in impairing the completion of mitochondrial DNA replication PMID: 20577816
  3. MTERF-domain of human MTERF3 forms a half-doughnut-shaped right-handed superhelix. PMID: 20430012
  4. mTERFL is a novel mTERF family member and a serum-inhibitory factor probably participating in the regulation of cell growth PMID: 16226716
Subcellular Location
Mitochondrion. Mitochondrion matrix, mitochondrion nucleoid.
Protein Families
MTERF family
Tissue Specificity
Expressed in skeletal muscle, heart, liver and pancreas.
Database Links

HGNC: 30779

OMIM: 616929

KEGG: hsa:80298

STRING: 9606.ENSP00000240050

UniGene: Hs.5009

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