Recombinant Mouse Autophagy-related protein 16-2 (Atg16l2)

Code CSB-YP757138MO
MSDS
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Source Yeast
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Code CSB-EP757138MO
MSDS
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Source E.coli
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Code CSB-EP757138MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP757138MO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP757138MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Atg16l2
Uniprot No.
Alternative Names
Atg16l2Autophagy-related protein 16-2; APG16-like 2
Species
Mus musculus (Mouse)
Expression Region
1-623
Target Protein Sequence
MAGPGAPCDP CAPAAVWKRH IVRQLRHRDR TQKALFLELV PAYNHLLEKA ELLAKFSEKL KSEPKDAIST RHEDWREEVS GTGPDQVSSP ASLRVKWQQE KKGLQLVCGE MAYQVVKKSA ALDTLQSQLE ERQDRLEALQ ACVVQLQEAR AQQSRQLEER QAENAAQREA YETLLQQAVH QEAALRRLQE EARDLLEQLV QRKARAAAER NLRNERRERA NQALVSQELK KAAKRTVSIS EIPNTLEDGT KEETVALAPA ALPEFSESET CEKWKRPFRS ASATSLTLSR CVDVVKGLLD FKKRRGHSVG GAPEQRYQSI PVCVSAQIPS QAQDVLDAHL SEVNAVCFGP NSSLLATGGA DRLIHLWNVV GGRLEANQTL EGAGGSITSV DFDPSGSQVL AATYNQAAQL WKVGETQSKE TLSGHKDKVT AAKFKLTRHQ AVTGSRDRTV KEWDLGRAYC SRTINVLSYC NDVVCGDHII ISGHNDQKIR FWDSRGPHCI QVIPVQGRVT SLHLSYDQLH LLSCSRDNTL KVIDLRISNI RQVFRADGFK CSSDWTKAVF SPDRSYALAG SSNGDLYIWD VNTGKLETSL QGPHCTAVNA VAWCFSGNHV VSVDQGRKVV LWH
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May play a role in regulating epithelial homeostasis in an ATG16L1-dependent manner.
Gene References into Functions
  1. IKKalpha, which may control autophagic protein degradation through its interaction with ATG16L2, plays a critical role in maintaining pancreatic acinar cell homeostasis, whose dysregulation promotes pancreatitis through p62 aggregate accumulation PMID: 23563314
  2. Despite forming the Atg12-Atg5-Atg16L2 complex, Atg16L2 is not recruited to phagophores and is mostly present in the cytosol. PMID: 22082872
Subcellular Location
Cytoplasm, cytosol.
Protein Families
WD repeat ATG16 family
Tissue Specificity
Widely expressed.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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