Recombinant Mouse BPI fold-containing family B member 1 (Bpifb1)

Code CSB-YP720239MO
MSDS
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Source Yeast
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Code CSB-EP720239MO
MSDS
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Source E.coli
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Code CSB-EP720239MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP720239MO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP720239MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Bpifb1
Uniprot No.
Alternative Names
Bpifb1; Lplunc1BPI fold-containing family B member 1; Long palate; lung and nasal epithelium carcinoma-associated protein 1
Species
Mus musculus (Mouse)
Expression Region
22-474
Target Protein Sequence
NVYPPAVLN LGPEVIQKHL TQALKDHDAT AILQELPLLR AMQDKSGSIP ILDSFVHTVL RYIIWMKVTS ANILQLDVQP STYDQELVVR IPLDMVAGLN TPLIKTIVEF QMSTEVQALI RVERSKSGPA HLNLSDCSSN ESTLRLSLLH KLSFVVNSLA KNVMNLLVPA LPQIVKNHLC PVIQQAFDDM YEDFLRLTTA PIALSPGALE FGLLSPAIQD SNILLNLKAK LLDSQARVTN WFNNSATSLM ETTPDRAPFS LTVRQDLVNA IVTTLVPKEE LVILLRFVIP DVARQLQMDI KEINAEAANK LGPTQMLKIF THSTPHIVLN EGSARAAQSV VLEVFPTNTD VRPFFSLGIE ASYEAQFFTE DNRLMLNFNN VSIERIKLMI SDIKLFDPEV LKDTLTKILE YTLLPNENGK LRTGVPMSMS KALGYEKAMW SVSKGALKLT PASS
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS. May be involved in formation of the left-right axis in the node of the developing embryo.
Gene References into Functions
  1. BPIFB1 is a novel regulator of MUC5B expression in airway mucosa. PMID: 28851744
  2. Bpifb1 mRNA is upregulated in parotid acinar cells in NOD mice, but its expression is not related to the onset of diabetes. These findings suggest that high expression levels of Bpifb1 might predict disease traits before the onset of autoimmunity. PMID: 26769076
  3. Autoimmunity targeting the lung-specific antigen BPIFB1 may contribute to the pathogenesis of interstitial lung disease. PMID: 24107778
  4. Knowledge of the complex expression patterns of BPIF proteins in these regions will allow the use of tractable mouse models of disease to dissect their function. PMID: 22986921
  5. CETP inhibitor torcetrapib promotes reverse cholesterol transport in obese insulin-resistant CETP-ApoB100 transgenic mice PMID: 22212222
  6. a novel gene LPlunc1, a member of BPI/PLUNC gene superfamily, which is asymmetrically expressed in the developing mouse node [LPlunc1 protein] PMID: 14745963

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Subcellular Location
Secreted.
Protein Families
BPI/LBP/Plunc superfamily, Plunc family
Tissue Specificity
Expressed in tongue, lung, thymus, and stomach. Expressed in epithelia of palate, anterior pharynx, trachea and upper bronchi. Expressed in distal tip of papillae in the anterior third of the tongue and in serous cells of von Ebner glands in the posterior
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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