Recombinant Mouse Adhesion G protein-coupled receptor B3 (Adgrb3), partial

Code CSB-YP773948MO
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Source Yeast
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Code CSB-EP773948MO
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Source E.coli
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Code CSB-EP773948MO-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP773948MO
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Source Baculovirus
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Code CSB-MP773948MO
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Adgrb3
Uniprot No.
Alternative Names
Adgrb3; Bai3Adhesion G protein-coupled receptor B3; Brain-specific angiogenesis inhibitor 3
Species
Mus musculus (Mouse)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity. Promotes myoblast fusion through ELMO/DOCK1.
Gene References into Functions
  1. Signal transduction via C1qL1-BAI3 interaction is required for motor learning, triggers pruting of surplus cerebellar climbing fibers, and is required to maintain climbing fiber synapses. PMID: 25611509
  2. G-protein coupled receptor BAI3 promotes myoblast fusion in vertebrates. PMID: 24567399
  3. results reveal that the BAI3 receptor controls dendritic arborization growth and branching in cultured neurons. PMID: 23628982
  4. Two transcripts with significant regulation from days 7 to 28 in the 1-methyl-4-phenyl-tetrahydropyridine treated groups are identified: brain specific angiogenesis inhibitor associated protein 3 (Baiap3) and breast carcinoma amplified sequence 1 (Bcas1). PMID: 21514331
  5. C1ql proteins are secreted signaling molecules that bind to BAI3 and act, at least in part, to regulate synapse formation and/or maintenance. PMID: 21262840

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Tissue Specificity
Brain-specific expression.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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