Recombinant Mouse Complement C1q subcomponent subunit B (C1qb)

Code CSB-YP003638MO
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Source Yeast
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Code CSB-EP003638MO
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Source E.coli
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Code CSB-BP003638MO
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Source Baculovirus
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Code CSB-MP003638MO
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
C1qb
Uniprot No.
Alternative Names
C1qbComplement C1q subcomponent subunit B
Species
Mus musculus (Mouse)
Expression Region
26-253
Target Protein Sequence
QSSCT GPPGIPGIPG VPGVPGSDGQ PGTPGIKGEK GLPGLAGDLG EFGEKGDPGI PGTPGKVGPK GPVGPKGTPG PSGPRGPKGD SGDYGATQKV AFSALRTINS PLRPNQVIRF EKVITNANEN YEPRNGKFTC KVPGLYYFTY HASSRGNLCV NLVRGRDRDS MQKVVTFCDY AQNTFQVTTG GVVLKLEQEE VVHLQATDKN SLLGIEGANS IFTGFLLFPD MDA
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Gene References into Functions
  1. The mRNA levels of H2-d1 in the prefrontal cortex, hippocampus, and hypothalamus and C1qb in the hippocampus of the DBA/2 J strain were significantly down-regulated as compared to those in the C57BL/6 J strain PMID: 25895500
Subcellular Location
Secreted.
Tissue Specificity
Highest expression in thioglycolate-activated peritoneal macrophages. Also found in spleen, thymus and heart. Very weak expression liver, kidney, lung and intestine.
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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