Recombinant Mouse Dual specificity protein phosphatase 8 (Dusp8)

Code CSB-YP007261MO
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP007261MO
MSDS
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Source E.coli
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Code CSB-EP007261MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP007261MO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP007261MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Dusp8
Uniprot No.
Alternative Names
Dusp8; Nttp1; Dual specificity protein phosphatase 8; EC 3.1.3.16; EC 3.1.3.48; Neuronal tyrosine threonine phosphatase 1
Species
Mus musculus (Mouse)
Expression Region
1-663
Target Protein Sequence
MAGDRLPRKV MDAKKLASLL RGGPGGPLVI DSRSFVEYNS CHVLSSVNIC CSKLVKRRLQ QGKVTIAELI QPATRSQVDA TEPQDVVVYD QSTRDASVLA ADSFLSILLS KLDGCFDSVA ILTGGFATFS SCFPGLCEGK PATLPSMSLS QPCLPVPSVG LTRILPHLYL GSQKDVLNKD LMTQNGISYV LNASNSCPKP DFICESRFMR IPINDNYCEK LLPWLDKSIE FIDKAKLSSC QVIVHCLAGI SRSATIAIAY IMKTMGMSSD DAYRFVKDRR PSISPNFNFL GQLLEYERSL KLLAALQTDG PHLGTPEPLM GPAAGIPLPR LPPSTSESAA TGSEAATAAR EGSPSAGGDA PIPSTAPATS ALQQGLRGLH LSSDRLQDTN RLKRSFSLDI KSAYAPSRRP DFPGPPDPGE APKLCKLDSP SGGTLGLPSP SPDSPDSVPE CRPRPRRRRP PASSPARSPA HGLGLNFGDT ARQTPRHGLS ALSAPGLPGP GQPAGPGGWV PPLDSPGTPS PDGPWCFSPE GAQGPGAVFS AFGRVSAGAP GPGNSSSSGG GGGGGGGGGG GGGGGGSSSS NSSSSSSSSS SSSSSSSSSS DLRRRDVRTG WPEEPAADAQ FKRRSCQMEF EEGMVEGRAR GEELAALGKQ TSFSGSVEVI EVS
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Has phosphatase activity with synthetic phosphatase substrates and negatively regulates mitogen-activated protein kinase activity, presumably by catalysing their dephosphorylation. Expected to display protein phosphatase activity toward phosphotyrosine, phosphoserine and phosphothreonine residues (Probable).
Gene References into Functions
  1. DUSP8 controls stress-induced ERK1/2 signaling in cardiac myocytes. PMID: 27225478
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily
Tissue Specificity
Expressed predominantly in brain and lung.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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