Recombinant Mouse Protein CTLA-2-alpha (Ctla2a)

Code CSB-YP320097MO
MSDS
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Source Yeast
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Code CSB-EP320097MO
MSDS
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Source E.coli
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Code CSB-EP320097MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP320097MO
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP320097MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Ctla2a
Uniprot No.
Alternative Names
Ctla2aProtein CTLA-2-alpha; Cytotoxic T-lymphocyte-associated protein 2-alpha
Species
Mus musculus (Mouse)
Expression Region
28-137
Target Protein Sequence
AAP PPDPSLDNEW KEWKTKFAKA YNLNEERHRR LVWEENKKKI EAHNADYEQG KTSFYMGLNQ FSDLTPEEFK TNCYGNSLNR GEMAPDLPEY EDLGKNSYLT PGRAQPE
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Not known, expressed in activated T-cell.
Gene References into Functions
  1. CTLA-2 secretion is induced by dendritic cells to enhance regulatory T cell conversion after administration of cholera toxin and cAMP PMID: 28759565
  2. that the fine equilibrium between synthesis and secretion of cathespin L and CTLA-2alpha is part of the brain processes to maintain normal growth and development PMID: 27586811
  3. Double immunofluorescence analysis showed that CTLA-2alpha was co-localized with cathepsin L, cathepsin C, and TINAGL1 in placenta. PMID: 25514977
  4. cAMP increases CTLA-2alpha expression in murine lymphoma and cardiac fibroblasts, and this increase in CTLA-2alpha contributes to cAMP/PKA-promoted apoptosis by mechanisms that are independent of the ability of CTLA-2alpha to inhibit cathepsin L. PMID: 21620962
Subcellular Location
Secreted.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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