Your Good Partner in Biology Research
Tel : 301-363-4651
Your Good Partner in Biology Research
| Code | CSB-YP020054MO |
| Product Type | Recombinant Protein |
| Size | US$2959 |
| Uniprot No. | O89026 |
| Relevance | Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development.Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1.In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. Plays a role in the regulation of cell migration via its interaction with MYO9B; inhibits MYO9B-mediated stimulation of RHOA GTPase activity, and thereby leads to increased levels of active, GTP-bound RHOA. May be required for lung development |
| Image |
|
| Storage Buffer | Tris-based buffer，50% glycerol |
| Species | Mus musculus (Mouse) |
| Purity | Greater than 90% as determined by SDS-PAGE. |
| Sequence | YRHRKKRNGLTSTYAGIRKVPSFTFTPTVTYQRGGEAVSSGGRPGLLNISEPATQPWLADTWPNTGNNHNDCSINCCTAGNGNSDSNLTTYSRPADCIANYNNQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQANLSNNMNNGAGDSSEKHWKPPGQQKPEVAPIQYNIMEQNKLNKDYRANDTIPPTIPYNQSYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKAPKQGGMNWADLLPPPPAHPPPHSNSEEYNMSVDESYDQEMPCPVPPAPMYLQQDELQEEEDERGPTPPVRGAASSPAAVSYSHQSTATLTPSPQEELQPMLQDCPEDLGHMPHPPDRRRQPVSPPPPPRPISPPHTYGYISGPLVSDMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEEDNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDAAGRRHFHASQCPRPTSPVSTDSNMSAVVIQKARPAKKQKHQPGHLRREAYADDLPPPPVPPPAIKSPTVQSKAQLEVRPVMVPKLASIEARTDRSSDRKGGSYKGREALDGRQVTDLRTNPSDPREAQEQPNDGKGRGTRQPKRDLPPAKTHLGQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQANVGRRNMAEMQVLGGFERGDENNEELEETES |
| Research Area | Cancer |
| Source | Yeast |
| Gene Names | Robo1 |
| Protein Names | Dutt1 |
| Expression Region | 880-1612aa |
| Tag Info | N-terminal 6xHis-tagged |
| Mol. Weight | 82.0 kDa |
| Protein Description | Partial |
| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development |
| Subcellular Location | Cell membrane, Single-pass type I membrane protein, Cell projection, axon |
| Protein Families | Immunoglobulin superfamily, ROBO family |
| Tissue Specificity | Detected in embryonic thalamus neurons (at protein level) (PubMed:24560577). Expressed in embryonal spinal chord. Expressed in embryonal lung, and in adult lung bronchial epithelial cells of large proximal airways. |
| Database Links |
KEGG: mmu:19876 STRING: 10090.ENSMUSP00000023600 UniGene: Mm.310772 |
Robo1 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-MP020054MO | Recombinant Mouse Roundabout homolog 1(Robo1) ,partial | Mammalian cell |
| CSB-EP020054MO CSB-BP020054MO |
Recombinant Mouse Roundabout homolog 1(Robo1) ,partial | E.coli Baculovirus |
Recombinant Human Hydroxymethylglutaryl-CoA lyase, mitochondrial(HMGCL)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Mouse Ras-related protein Rab-10(Rab10)
Express system: E.coli
Species: Mus musculus (Mouse)
Recombinant Human Oxytocin-neurophysin 1(OXT),partial
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Glycogen phosphorylase, liver form(PYGL),partial
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human T cell receptor alpha constant(TRAC)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Cell cycle checkpoint protein RAD1(RAD1)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Mitochondrial import receptor subunit TOM40 homolog(TOMM40)
Express system: E.coli
Species: Homo sapiens (Human)
