Recombinant Mouse SPARC-related modular calcium-binding protein 2 (Smoc2)

Code CSB-YP807488MO
MSDS
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Source Yeast
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Code CSB-EP807488MO
MSDS
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Source E.coli
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Code CSB-EP807488MO-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP807488MO
MSDS
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Source Baculovirus
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Code CSB-MP807488MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Smoc2
Uniprot No.
Alternative Names
Smoc2; SPARC-related modular calcium-binding protein 2; Secreted modular calcium-binding protein 2; SMOC-2
Species
Mus musculus (Mouse)
Expression Region
22-447
Target Protein Sequence
QKFSALTFL RVDQDKDRDC SLDCPSSPQK PLCASDGRTF LSRCEFQRAK CKDPQLEIAH RGNCKDVSRC VAERKYTQEQ ARKEFQQVFI PECNDDGTYS QVQCHSYTGY CWCVTPNGRP ISGTAVAHKT PRCPGSINEK VPQREGAGKA DDAAAPALET QPQGDEEDIA SRYPTLWTEQ VKSRQNKTNK NSASSCDQEH QSALEEAKQP KNDNVVIPEC AHGGLYKPVQ CHPSTGYCWC VLVDTGRPIP GTSTRYEQPK CDNTARAHPA KARDLYKNRP LQGCPGAKKH EFLTSVLDAL STDMVHAVSD PSSSSGRLSE PDPSHTLEER VVHWYFKLLD KNSSGDIGKK EIKPFKRFLR KKSKPKKCVK KFVEYCDMNN DKSITVQELM GCLGVTREEG KANTRKRHTP RGNAESSSSN RQPRKQG
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Can stimulate endothelial cell proliferation, migration, as well as angiogenesis. Promotes matrix assembly and cell adhesiveness.
Gene References into Functions
  1. By using microRNA array, we identified a large number of microRNAs that showed different expression between wild-type Runx2 group and mutant groups. The aim of this study is to find out the effect of mmu-miR-1963, which was downregulated in all mutant Runx2 groups, on the ameloblast differentiation of LS8 cells PMID: 29233684
  2. SMOC1 and SMOC2 may mediate intercellular signaling and cell type-specific differentiation during gonad and reproductive tract development PMID: 19842175
  3. SMOC-2 is a novel angiogenic factor that potentiates angiogenic effects of growth factors PMID: 16774925
  4. SMOC-2 contributes to cell cycle progression by maintaining ILK activity during G1. PMID: 17989364
  5. SMOC-2, like other members of the BM40/SPARC family, acts as a regulator of cell-matrix interactions. PMID: 18582461
  6. results indicate that Smoc2 is a novel transcriptional target of activated Ahr. Perturbation of Smoc2 expression may mediate the adverse developmental effects of environmental aryl-hydrocarbon exposure PMID: 19146932

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Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane.
Tissue Specificity
Strongly expressed in ovary, followed by heart, muscle, spleen, brain, thymus, lung, liver, kidney, spleen, testis, ovary and skeletal muscle.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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