Recombinant Mouse Tyrosine-protein phosphatase non-receptor type 7 (Ptpn7)

Code CSB-YP805341MO
MSDS
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Source Yeast
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Code CSB-EP805341MO
MSDS
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Source E.coli
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Code CSB-EP805341MO-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP805341MO
MSDS
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Source Baculovirus
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Code CSB-MP805341MO
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Ptpn7
Uniprot No.
Alternative Names
Ptpn7; Tyrosine-protein phosphatase non-receptor type 7; EC 3.1.3.48; Hematopoietic protein-tyrosine phosphatase; HEPTP
Species
Mus musculus (Mouse)
Expression Region
1-359
Target Protein Sequence
MVQACEGRSR AQLPTLSLGA DMTQPPPTKA PAKKHVRLQE RRGSSVALML DVQSLGTVEP ICSVNTPREV TLHFLRTAGH PLTRWTLQHQ PPSPKQLEEE FLKIPSNFVN PEDLDIPGHA SKDRYKTILP NPQSRVCLGR AQSQEDSDYI NANYIRGYDG KEKVYIATQG PMPNTVADFW EMVWQEDVSL IVMLTQLREG KEKCVHYWPT EEEAYGPFQI RIQDMKEHPE YTVRQLTIQH QQECRSVKHI LFSAWPDHQT PESAGPLLRL VAEVETPETA ANSGPIVVHC SAGIGRTGCF IATRIGCQQL KARGEVDILG IVCQLRLDRG GMIQTAEQYQ FLHHTLALYA AQLPPEPNP
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May play a role in the regulation of T and B-lymphocyte development and signal transduction.
Gene References into Functions
  1. PTPN7 as a negative regulator of TNF-alpha expression and the inflammatory response in macrophages PMID: 24265715
  2. beta(2)AR stimulation on a B cell phosphorylates and inactivates HePTP in a Gs/cAMP/PKA-dependent manner to release bound p38 MAPK, making more available for phosphorylation and subsequent IgE regulation. PMID: 19047375
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Note=Oxidized form is preferentially associated with actin cytoskeleton.
Protein Families
Protein-tyrosine phosphatase family, Non-receptor class subfamily
Tissue Specificity
Expressed in bone marrow-derived mast cells.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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