Recombinant Rat Caprin-1 (Caprin1)

Code CSB-YP711733RA
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP711733RA-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP711733RA
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP711733RA
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
Caprin1
Uniprot No.
Alternative Names
Caprin1; Gpiap1; Rng105Caprin-1; Cytoplasmic activation- and proliferation-associated protein 1; GPI-anchored protein p137; GPI-p137; p137GPI; RNA granule protein 105
Species
Rattus norvegicus (Rat)
Expression Region
2-707
Target Protein Sequence
PSATSHSGS GSKSSGPPPP SGSSGSEAAA GAAAPASQHP ATGTGAVQTE AMKQILGVID KKLRNLEKKK GKLDDYQERM NKGERLNQDQ LDAVSKYQEV TNNLEFAKEL QRSFMALSQD IQKTIKKTAR REQLMREEAE QKRLKTVLEL QYVLDKLGDD DVRTDLKQGL SGVPILSEEE LSLLDEFYKL VDPERDMSLR LNEQYEHASI HLWDLLEGKE KPVCGTTYKA LKEIVERVFQ SNYFDSTHNH QNGLCEEEEA ASAPIVEDQV AEAEPEPTEE YTEQSEVEST EYVNRQFMAE TQFSSGEKEQ VDEWAVETVE VVNSLQQQPQ AASPSVPEPH SLTPVAQSDP LVRRQRVQDL MAQMQGPYNF IQDSMLDFEN QTLDPAIVSA QPMNPTQNMD MPQLVCPQVH SESRLAQSNQ VPVQPEATQV PLVSSTSEGY TASQPLYQPS HAAEQRPQKE PIDQIQATIS LNTEQTTASS SLPAASQPQV FQAGASKPLH SSGINVNAAP FQSMQTVFNM NAPVPPVNEP ETLKQQSQYQ ASYNQSFSSQ PHQVEQTELQ QDQLQTVVGT YHGSQDQPHQ VPGNHQQPPQ QSTGFPRSSQ PYYNSRGVSR GGSRGARGLM NGYRGPANGF RGGYDGYRSS FSNTPNSGYT QSQFNAPRDY SGYQRDGYQQ NFKRGSGQSG PRGAPRGRGG PPRPNRGMPQ MNTQQVN
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs.
Gene References into Functions
  1. RNG105 is a translational repressor in the RNA granules and provide insight into the link between RNG105 dynamics and local translational regulation. PMID: 15858068
Subcellular Location
Cytoplasm, cytosol. Cell projection, dendrite. Cell projection, lamellipodium.
Protein Families
Caprin family
Tissue Specificity
Expressed in hippocampal and neocortical pyramidal neurons, but not in Purkinje cells.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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