Recombinant Rat Myosin-binding protein C, slow-type (Mybpc1)

Code CSB-YP717389RA
MSDS
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Source Yeast
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Code CSB-EP717389RA
MSDS
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Source E.coli
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Code CSB-EP717389RA-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP717389RA
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP717389RA
MSDS
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Source Mammalian cell
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Product Details

Purity
≥85% (SDS-PAGE)
Target Names
Mybpc1
Uniprot No.
Alternative Names
Mybpc1; Myosin-binding protein C; slow-type; Slow MyBP-C; C-protein; skeletal muscle slow isoform; Fragment
Species
Rattus norvegicus (Rat)
Expression Region
1-621
Target Protein Sequence
EEIVPGPKSR YRIKVEGKKH TLIIEGATKA DSAEYSVMTT GGQSSAKLSV DLRPLKITTP LTDQTVKLGK EVCLKCEISE NVPGKWTKNG LPVQEGERLK VVHKGRIHKL VIANALIEDE GEYVFTPDAI TVPLVCQIHV IDPPKIILDG LEADNTVTVI AGSKLRLEIP VTGEPPPKAI WSRADKAIME GSGRIRAESY PDSSTLVIDV AERDDSGVYN INLKNEAGEA HASIKLRLWI SLILRLAPNV TEVGDDWCIM NWEPPVYDGG SPILGYFIER KKKQSSRWMR LNFDLCKETT FEPKKMIEGV AYEVRIFAVN AIGISKPSMP SKPFVPLAVT SPPTLLAVDS VTDSSVTMKW RPPDQIGAAG LSGYVLEYCF EGSTSAKQSN ENGEAANDLP AEDWSLQTQT GSTRPKFTIT GLPTDAKIFV RVKAINAAGA SETKYYSQPI LVKEIIEPPK IRIPRHLKQT YIRRVGEAVN LVIPFQGKPR PELTWKKDGA EIDKNQINIR NSETDTIIFI RKAERSHSGK YDLEVKVDKY VENASIDIQI VDRPGPPQAV TIEDVWGENV ALTWTPPKDD GNAAITGYTI QKADKKSMEW FAVIEHYHRT NATITELVIG N
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. Slow skeletal protein that binds to both myosin and actin. In vitro, binds to native thin filaments and modifies the activity of actin-activated myosin ATPase. May modulate muscle contraction or may play a more structural role.
Gene References into Functions
  1. Myosin-binding protein C (MyBP-C) has roles in cardiac muscle and contractility [review] PMID: 15098652
  2. These findings suggest that C-protein-induced EAM is formed by activation of C-protein-specific T cells along with antibodies against conformational epitopes in C-protein but that there are undetermined factors related to the disease progression. PMID: 17900708
  3. The distribution of MyBP-C in the A-bands of cardiac and skeletal muscles and compare this to the A-band structure in cardiac muscle of MyBP-C-deficient mice, was investigated. PMID: 18817784
Protein Families
Immunoglobulin superfamily, MyBP family
Database Links

KEGG: rno:362867

UniGene: Rn.9153

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