Recombinant Rat Neurogenic differentiation factor 1(Neurod1)

Code CSB-YP731042RA
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Source Yeast
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Code CSB-EP731042RA
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Source E.coli
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Code CSB-EP731042RA-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP731042RA
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Source Baculovirus
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Code CSB-MP731042RA
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names Neurod1
Uniprot No. Q64289
Alternative Names Neurod1; Neurod; Neurogenic differentiation factor 1; NeuroD1; Basic helix-loop-helix factor 1; BHF-1
Species Rattus norvegicus (Rat)
Expression Region 1-357
Target Protein Sequence MTKSYSESGL MGEPQPQGPP SWTDECLSSQ DEEHEADKKE DELEAMNAEE DSLRNGGEEE DEDEDLEEEE EEEEEEDDQK PKRRGPKKKK MTKARLERFK LRRMKANARE RNRMHGLNAA LDNLRKVVPC YSKTQKLSKI ETLRLAKNYI WALSEILRSG KSPDLVSFVQ TLCKGLSQPT TNLVAGCLQL NPRTFLPEQN PDMPPHLPTA SASFPVHPYS YQSPGLPSPP YGTMDSSHVF HVKPPPHAYS AALEPFFESP LTDCTSPSFD GPLSPPLSIN GNFSFKHEPS TEFEKNYAFT MHYPAATLAG PQSHGSIFSS GAAAPRCEIP IDNIMSFDSH SHHERVMSAQ LNAIFHD
Protein Length full length protein
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Data

Function Acts as a transcriptional activator
Gene References into Functions
  1. NeuroD1, an essential regulator of glutamatergic neuronal differentiation, as a new mRNA target interacting with FMRP in co-immunoprecipitation experiments. PMID: 24338128
  2. inhibition of neuroD/BETA2 mediated transcriptional activation induces c-myc expression (neuroD/BETA2) PMID: 11799123
  3. the expression of neuroD mRNA during the postnatal development of euthyroid and hypothyroid rats, compared with that of neurotrophin-3, a marker of granular neurone differentiation PMID: 12242038
  4. glucose-stimulation of the MEK-ERK signalling pathway influences NeuroD1 activity at least partially through effects on sub-cellular localization PMID: 12297313
  5. the SREBP-1c.BETA2.E47 complex is in a DNA looping structure which is required for efficient recruitment of CREB-binding protein/p300 PMID: 16055439
  6. The nuclear import of NeuroD1 and E47 is energy-dependent and involves the Ran-mediated pathway. PMID: 19272376

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Subcellular Location Cytoplasm, Nucleus
Database Links

KEGG: rno:29458

STRING: 10116.ENSRNOP00000007662

UniGene: Rn.44289

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