Recombinant Rat Vesicle-associated membrane protein 1 (Vamp1), partial

1. Our study uncovers the postsynaptic function of the SNAP25-VAMP1-syntaxin4 complex in mediating the constitutive exocytosis of NMDA receptors, suggesting that this SNARE complex is involved in excitatory synaptic transmission PMID: 27791016
2. differential sorting of the rat v-SNARE splice isoforms VAMP-1a and -1b PMID: 28314111
3. residue 48 of VAMP1 varies frequently between M and I across seventeen closely related primate species, suggesting a potential selective pressure from members of BoNTs for resistance in vertebrates. PMID: 25010769
4. syntaxin 1 and vesicle-associated membrane protein 1 are more suitable targets to abolish functional soluble N-ethylmaleimide-sensitive factor attachment protein receptor complexes PMID: 24604356
5. distribution of SNAP25, VAMP1 and VAMP2 in adult deep cerebellar nuclei differs significantly from that found in newborn DCN and administration of E2 in the newborn DCN affected synaptic density and also changed their distribution PMID: 24534378
6. The results of this study provided the first evidence showing the dual role of SNAP25 and synaptobrevin in both exocytosis and slow endocytosis at conventional synapses. PMID: 23699527
7. multiple domains outside the R-SNARE of tomosyn are critical to the efficacy of inhibition by tomosyn on exocytotic secretion PMID: 21330375
8. Syntaxin-4 and VAMP-1 and VAMP-2 regulate cardiac myocyte exocytosis of ANP. PMID: 20801128
9. the trigger site in synaptobrevin is crucial for productive SNARE zippering PMID: 20406821
10. Data report the structure and the assembling behavior of VAMP1 incorporated in a lipid monolayer at an air-water interface which mimics the membrane environment, and show that the structure of VAMP1 is clearly controlled by protein-lipid interactions. PMID: 20085749
11. VAMP1 mRNA is transiently decreased during nerve regeneration of the facial motor nucleus after axotomy. PMID: 12191731
12. vesicle-associated membrane protein 1 is involved in secretion of polypeptides from the choroid plexus epithelium. PMID: 12559091
13. is the main isoform in particular brain areas (e.g. zona incerta at the subthalamus or nerve terminals surrounding thalamic neurons) PMID: 16169186
14. Treatment with botulinum neurotoxins A and B strongly reduced somatodendritic dopamine release, thus demonstrating the requirement for SNARE proteins SNAP-25 and synaptobrevin. PMID: 16539689
15. Data show that synaptobrevin in proteoliposomes as well as in purified synaptic vesicles is constitutively active. PMID: 17360966
16. CGRP was found to occur in the majority of neurons from rat trigeminal ganglia, together with the three exocytotic SNAREs [SNAP25, syntaxin 1 and the synaptobrevin (Sbr, also known as VAMP) isoforms] and synaptotagmin. PMID: 17666428
17. Several species of Vamp1 were amplified from a brain cDNA library including a full length clone of Vamp1as and a novel splice variant we termed Vamp1nv that was expressed in each of the cochlear nucleus subdivisions. PMID: 18655825

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KEGG: rno:25624

STRING: 10116.ENSRNOP00000025081

UniGene: Rn.31977