Recombinant Saccharomyces cerevisiae ADIPOR-like receptor IZH2 (IZH2), partial

Code CSB-YP622480SVG1
MSDS
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Source Yeast
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Code CSB-EP622480SVG1
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Source E.coli
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Code CSB-EP622480SVG1-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP622480SVG1
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Source Baculovirus
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Code CSB-MP622480SVG1
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
IZH2
Uniprot No.
Alternative Names
IZH2; PHO36; YOL002C; UND327; ADIPOR-like receptor IZH2; Phosphate metabolism protein 36
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Probable receptor, which is involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation.
Gene References into Functions
  1. Studied yeast Izh2 protein and zinc ion homeostasis and in the regulation of lipid and phosphate metabolism. PMID: 26067383
  2. Double disruption of the EOS1 and IZH2 genes yielded a slow-growth phenotype, suggesting that the two proteins are involved in related cellular processes. PMID: 20146743
  3. Data show that the protein encoded by ORE20/PHO36 (YOL002c) is an osmotin binding plasma membrane protein that is required for full sensitivity to osmotin. PMID: 15664187
  4. Data show that overproduction of Izh2p prevents the iron-dependent induction of the Fet3p component of the high-affinity iron-uptake system and is deleterious for growth in iron-limited medium. PMID: 17553578
  5. Izh2p negatively regulates functionally divergent genes through a CCCTC promoter motif. PMID: 18625204
  6. Izh2p produces sphingoid bases, bioactive lipids which probably function as the second messenger responsible for the repressive effect of Izh2p on iron-uptake gene FET3. PMID: 19066337

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Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
ADIPOR family
Database Links

KEGG: sce:YOL002C

STRING: 4932.YOL002C

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