Recombinant Schizosaccharomyces pombe Exosome complex component rrp43(rrp43)

Product Type Recombinant Protein
Uniprot No. Q10205
Abbreviation rrp43
Species Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Gene Names rrp43
Protein Names Recommended name: Exosome complex component rrp43 Alternative name(s): Ribosomal RNA-processing protein 43
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Function Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and in RNA surveillance pathways, preventing translation of aberrant mRNAs. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes. ski6 is part of the hexameric ring of RNase PH domain-containing subunits proposed to form a central channel which threads RNA substrates for degradation (By similarity).
Subcellular Location Cytoplasm, Nucleus, nucleolus
Protein Families RNase PH family
Database Links

KEGG: spo:SPBC17D1.03c

STRING: 4896.SPBC17D1.03c.1

Product Details for Different Expression Systems

Product Name Recombinant Schizosaccharomyces pombe Exosome complex component rrp43(rrp43),Yeast
Code CSB-YP604571SXV
Size Pls inquiry other sizes
Source Yeast
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MKTVSGVKQL SFTPSIFKKI TPEQYLSHLL NQDVRSDGRS VSEFREIVIN DNCISTANGS AIIRAGENVF VCGIKAEIAE PFENSPNEGW IVPNLELSPL CSSKFKPGPP SDLAQVVSQE LHQTLQQSNL INLQSLCIFE KKAAWVLYAD IICLNYDGSA FDYAWAALFA ALKTVKLPTA VWDEDLERVI CASTLTRPVQ LSTEVRSFSW SVFDDKLLAD PTDEEEDLST EFLTIMLNSS KNIVKIIKLG GTHIQPLLLK KCIEVARSKF
Expression Region 1-270
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
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Product Name Recombinant Schizosaccharomyces pombe Exosome complex component rrp43(rrp43),E.coli
Code CSB-EP604571SXV
Size Pls inquiry other sizes
Source E.coli
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-SUMO-tagged and C-terminal Myc-tagged
N-terminal His-B2M-tagged and C-terminal Myc-tagged
N-terminal His-GST-tagged and C-terminal Myc-tagged
N-terminal His-tagged
N-terminal His-SUMO-tagged
N-terminal His-B2M-tagged
N-terminal His-GST-tagged
N-terminal GST-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MKTVSGVKQL SFTPSIFKKI TPEQYLSHLL NQDVRSDGRS VSEFREIVIN DNCISTANGS AIIRAGENVF VCGIKAEIAE PFENSPNEGW IVPNLELSPL CSSKFKPGPP SDLAQVVSQE LHQTLQQSNL INLQSLCIFE KKAAWVLYAD IICLNYDGSA FDYAWAALFA ALKTVKLPTA VWDEDLERVI CASTLTRPVQ LSTEVRSFSW SVFDDKLLAD PTDEEEDLST EFLTIMLNSS KNIVKIIKLG GTHIQPLLLK KCIEVARSKF
Expression Region 1-270
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Schizosaccharomyces pombe Exosome complex component rrp43(rrp43),Baculovirus
Code CSB-BP604571SXV
Size Pls inquiry other sizes
Source Baculovirus
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MKTVSGVKQL SFTPSIFKKI TPEQYLSHLL NQDVRSDGRS VSEFREIVIN DNCISTANGS AIIRAGENVF VCGIKAEIAE PFENSPNEGW IVPNLELSPL CSSKFKPGPP SDLAQVVSQE LHQTLQQSNL INLQSLCIFE KKAAWVLYAD IICLNYDGSA FDYAWAALFA ALKTVKLPTA VWDEDLERVI CASTLTRPVQ LSTEVRSFSW SVFDDKLLAD PTDEEEDLST EFLTIMLNSS KNIVKIIKLG GTHIQPLLLK KCIEVARSKF
Expression Region 1-270
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat
Product Name Recombinant Schizosaccharomyces pombe Exosome complex component rrp43(rrp43),Mammalian cell
Code CSB-MP604571SXV
Size Pls inquiry other sizes
Source Mammalian cell
Purity >85% (SDS-PAGE)
Tag Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Sequence MKTVSGVKQL SFTPSIFKKI TPEQYLSHLL NQDVRSDGRS VSEFREIVIN DNCISTANGS AIIRAGENVF VCGIKAEIAE PFENSPNEGW IVPNLELSPL CSSKFKPGPP SDLAQVVSQE LHQTLQQSNL INLQSLCIFE KKAAWVLYAD IICLNYDGSA FDYAWAALFA ALKTVKLPTA VWDEDLERVI CASTLTRPVQ LSTEVRSFSW SVFDDKLLAD PTDEEEDLST EFLTIMLNSS KNIVKIIKLG GTHIQPLLLK KCIEVARSKF
Expression Region 1-270
Protein Description full length protein
Storage Buffer Tris-based buffer,50% glycerol
Still Have Questions? Leave a Message or Start an on-line Chat

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