AAMP Recombinant Monoclonal Antibody

Code CSB-RA581966A0HU
Size US$210
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  • Western blotting analysis using angio associated migratory cell protein antibody. Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with angio associated migratory cell protein antibody and HRP-conjugated goat anti-rabbit secondary antibody respectively.
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Product Details

Uniprot No.
Target Names
AAMP
Alternative Names
AAMP; Angio Associated Migratory Cell Protein; Angio-Associated Migratory Cell Protein
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Human AAMP protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Monoclonal
Isotype
Rabbit IgG
Clone No.
3B6
Purification Method
Affinity-chromatography
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Rabbit IgG in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway.
Gene References into Functions
  1. AAMP Regulates Endothelial Cell Migration and Angiogenesis Through RhoA/Rho Kinase Signaling. PMID: 26350504
  2. High levels of AAMP levels were associated with breast cancer progression and metastasis PMID: 23564791
  3. angio-associated migratory cell protein was identified as a novel interacting partner of both TPalpha and TPbeta isoforms of the thromboxane A2 receptor PMID: 21172430
  4. important functional role of AAMP in the migration of smooth muscle cells (SMCs), identifying AAMP as a potential target to limit lesion formation after injury. PMID: 18634987
  5. Data support a new function of AAMP in regulating innate immune responses initiated by the NLR protein Nod2. PMID: 19535145

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Subcellular Location
Cell membrane. Cytoplasm.
Tissue Specificity
Expressed in metastatic melanoma, liver, skin, kidney, heart, lung, lymph node, skeletal muscle and brain, and also in A2058 melanoma cells and activated T-cells (at protein level). Expressed in blood vessels. Strongly expressed in endothelial cells, cyto
Database Links

HGNC: 18

OMIM: 603488

KEGG: hsa:14

STRING: 9606.ENSP00000248450

UniGene: Hs.83347

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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