Code | CSB-RA008839A0HU |
Size | US$210 |
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The recombinant FOXO4 antibody is a monoclonal antibody made in vitro using the FOXO4 antibody genes that are typically expressed from a plasmid in a stable mammalian cell line. The genes coding for the FOXO4 antibody will ultimately assemble into a fully functional antibody after translation. The synthesized antibody is the recombinant antibody against FOXO4. It underwent purification using affinity-chromatography. This recombinant FOXO4 antibody is suitable for use in the ELISA to detect the FOXO4 protein from Human.
FOXO4 regulates the transcription of many genes involved in metabolism, cell cycle, apoptosis, and cellular homeostasis through transcriptional activity. It also controls cell responses to oxidative stress and anticancer therapy. Upon activation, FOXO4 induces an increased transcriptional activation of p21 and subsequent activation of cellular senescence. FOXO4 expression is inhibited by microRNAs in many types of cancer cells. The deregulation of FOXO4 is closely associated with the progression of several types of malignancies, senescence, and other disorders.
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