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| Code | CSB-RA971033A0HU |
| Size | US$210 |
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| Application | Recommended Dilution |
|---|---|
| WB | 1:500-1:2000 |
| IF | 1:50-1:200 |
| FC | 1:50-1:200 |
The MAS1L recombinant monoclonal antibody is produced through a process of genetic engineering that involves cloning and expression of the gene encoding for the MAS1L monoclonal antibody. The immunogen used to generate the MAS1L monoclonal antibody is the synthesized peptide derived from human MAS1L protein. The obtained MAS1L recombinant monoclonal antibody is purified using affinity chromatography to ensure high and purity. This MAS1L recombinant monoclonal antibody can specifically recognize and bind to the MAS1L protein. It has been validated for use in human and rat samples. Multiple applications including ELISA, WB, IF, and FC have been carried out to test the quality and specificity of the MAS1L recombinant monoclonal antibody.
MAS1L is primarily expressed in the adrenal gland, but is also found in other tissues including the brain, kidney, and heart. It is involved in the regulation of blood pressure and cardiovascular homeostasis through the renin-angiotensin system (RAS). MAS1L is activated by angiotensin-(1-7), a peptide hormone that opposes the effects of angiotensin II, which promotes vasoconstriction and raises blood pressure. Activation of MAS1L leads to vasodilation and a decrease in blood pressure. MAS1L has been found to be expressed on immune cells such as macrophages, and its activation has been shown to inhibit the release of inflammatory cytokines.
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