Code | CSB-RA978157A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
IHC | 1:50-1:200 |
IF | 1:20-1:200 |
To create the MYBBP1A recombinant monoclonal antibody, several steps are necessary. These include the harvest of the MYBBP1A monoclonal antibody, MYBBP1A monoclonal antibody gene sequencing, vector construction, and transfection of the constructed MYBBP1A monoclonal antibody gene-carrying vector into a host cell line for culture. The synthesized peptide from human MYBBP1A is used as an immunogen in the MYBBP1A monoclonal antibody production. The MYBBP1A recombinant monoclonal antibody is purified from the cell culture supernatant, and its specificity is evaluated through ELISA, IHC, and IF tests. It only reacts with human MYBBP1A protein.
The MYBBP1A is a transcriptional co-regulator that plays important roles in the regulation of gene expression, cell cycle progression, DNA repair, and apoptosis. MYBBP1A is involved in the regulation of gene expression by acting as a transcriptional co-regulator. It plays a role in the regulation of the cell cycle by interacting with E2F transcription factors. MYBBP1A interacts with the DNA repair protein Ku70 and is required for efficient non-homologous end-joining (NHEJ) repair of DNA double-strand breaks. Dysregulation of MYBBP1A activity has been implicated in various diseases, including cancer and neurological disorders.
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