PDCD7 Recombinant Monoclonal Antibody

Programmed cell death protein 7 (PDCD7), also known as apoptosis-related protein ES18, plays a role in cellular apoptotic pathways and has garnered interest among researchers investigating cell death mechanisms and related regulatory processes. Understanding PDCD7 expression and localization provides valuable insights into fundamental cell biology and may illuminate connections to broader physiological and pathological contexts.

This recombinant monoclonal antibody, clone 13D11, offers researchers the reliability that comes with sequence-defined production. Unlike traditional hybridoma-derived antibodies, recombinant technology ensures exceptional lot-to-lot consistency, meaning your experimental conditions and results remain comparable across studies and over time. The antibody is raised in rabbit against a synthesized peptide from human PDCD7, providing defined epitope recognition for human samples.

Validation studies demonstrate robust performance in both immunofluorescence and flow cytometry applications. In immunofluorescence experiments using SH-SY5Y neuroblastoma cells, the antibody produces clear staining at dilutions of 1:50 to 1:200, enabling visualization of PDCD7 localization when combined with DAPI counterstaining. Flow cytometry validation in HeLa cells confirms specific detection with distinct positive signal separation from isotype control, supporting quantitative analysis of PDCD7 expression at the single-cell level. These complementary applications give you flexibility to examine both spatial distribution and expression levels within your experimental workflow.

Supplied in a stabilized liquid format with glycerol for convenient long-term storage at -20°C or -80°C, this affinity-purified antibody is ready for immediate use in your cell biology research. Whether investigating apoptotic signaling pathways or characterizing PDCD7 expression patterns, this antibody provides the consistency and validated performance essential for reproducible results.