Rabbit anti-Human IgG Fc Antibody

Datasheet
Code CSB-PA00540E0Rb
Product Type Secondary Antibody
Size US$169Purchase it in Cusabio online store
(only available for customers from the US)
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Human IgG Fc fragment
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. InIgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and α-2,6 linked sialic acid residues.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method Caprylic Acid Ammonium Sulfate Precipitation purified
Isotype IgG
Clonality Polyclonal
Alias fragment crystallizable region
Protocols ELISA Protocol
Protocol
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
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