PCNA Monoclonal Antibody

Datasheet
Code CSB-MA000081M0m
Product Type Tag/Control Antibodies
Size US$200Purchase it in Cusabio online store
(only available for customers from the US)
Immunogen PCNA fusion protein
Raised in mouse
Tested Applications ELISA
Relevance Proliferating Cell Nuclear Antigen, commonly known as PCNA, is a protein that acts as a processivity factor for DNA polymerase δ in eukaryotic cells. This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. PCNA induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. It has to be loaded onto DNA in order to be able to stimulate APEX2. PCNA protein is highly conserved during evolution; the deduced amino acid sequences of rat and human differ by only 4 of 261 amino acids. PCNA has been used as loading control for proliferating cells. This antibody is a rabbit polyclonal antibody raised against an internal region of human PCNA.
Form liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%,protein G purifed
Isotype IgG1
Clonality monoclonal
Alias Cyclin, PCNA
Protocols ELISA Protocol
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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