Recombinant Bovine Dopamine beta-hydroxylase(DBH)

Code CSB-CF006518BO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P15101
Storage Buffer Tris-based buffer,50% glycerol
Species Bos taurus (Bovine)
Sequence MQVPSPSVREAASMYGTAVAVFLVILVAALQGSAPAESPFPFHIPLDPEGTLELSWNISYAQETIYFQLLVRELKAGVLFGMSDRGELENADLVVLWTDRDGAYFGDAWSDQKGQVHLDSQQDYQLLRAQRTPEGLYLLFKRPFGTCDPNDYLIEDGTVHLVYGFLEEPLRSLESINTSGLHTGLQRVQLLKPSIPKPALPADTRTMEIRAPDVLIPGQQTTYWCYVTELPDGFPRHHIVMYEPIVTEGNEALVHHMEVFQCAAEFETIPHFSGPCDSKMKPQRLNFCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRFLRLEVHYHNPLVITGRRDSSGIRLYYTAALRRFDAGIMELGLAYTPVMAIPPQETAFVLTGYCTDKCTQLALPASGIHIFASQLHTHLTGRKVVTVLARDGRETEIVNRDNHYSPHFQEIRMLKKVVSVQPGDVLITSCTYNTEDRRLATVGGFGILEEMCVNYVHYYPQTQLELCKSAVDPGFLHKYFRLVNRFNSEEVCTCPQASVPEQFASVPWNSFNREVLKALYGFAPISMHCNRSSAVRFQGEWNRQPLPEIVSRLEEPTPHCPASQAQSPAGPTVLNISGGKG
Source in vitro E.coli expression system
Gene Names DBH
Protein Names Recommended name: Dopamine beta-hydroxylase EC= 1.14.17.1 Alternative name(s): Dopamine beta-monooxygenase Cleaved into the following chain: 1. Soluble dopamine beta-hydroxylase
Expression Region 1-610
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Conversion of dopamine to noradrenaline.
Subcellular Location Soluble dopamine beta-hydroxylase: Cytoplasmic vesicle, secretory vesicle lumen, Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen, SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle membrane, Single-pass type II membrane protein, Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane, Single-pass type II membrane protein
Protein Families Copper type II ascorbate-dependent monooxygenase family
Tissue Specificity Detected in chromaffin granules in the adrenal medulla (at protein level) (PubMed:2620060, PubMed:843373, PubMed:4525162). Detected in adrenal medulla (PubMed:2620060).
Database Links

KEGG: bta:280758

STRING: 9913.ENSBTAP00000005924

UniGene: Bt.4481

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