Recombinant Bovine Dystroglycan(DAG1)

Code CSB-CF006488BO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O18738
Storage Buffer Tris-based buffer,50% glycerol
Species Bos taurus (Bovine)
Sequence HWPSEPSEAVRDWENQLEASMHSALSDLHETVPTVVGIPDGTAVVGRSFRVTIPTDLIASNGEVIKVSAAGKEALPSWLHWDPQSHTLEGLPLDTDKGVHYISVSAARLGANGSHVPQTSSVFSIEVYPEDHSEPQSLRAASPDPGEVVSLVCAADEPVTVLTVILDADLTKMTPKQRIDLLRRMRGFSEVEPHNMKLVPVVNNRLFDMSAFMAGPGNAKKVVENGALLSWKLGCCLNQNSVPDIRGVEVPAREGAMSAQLGYPVVGWHIANKKPSLPKRIRRQIHATPTPVTAIGPPTTAIQEPPSRIVPTPTSPAIAPPTETMAPPVRDPVPGKPTVTIRTRGAIIQTPTLGPIQPTRVSEAGTTVPSQIRPTMTIPGYMEPSTVTTPPTTTTKKPRVSTPRPATPSTDSSTTTTRRPTKKPRTSRPVPRVTTKAPITRLETASPATRMRTTTSGVPHGGEPNQRPELKNHIDRVDAWVGTYFEVKIPSDTFYDNEDTTTDKLKLTLKLREQQLVGEKSWVQFNSNSQLMYGLPDSSHVGKHEYFMHATDKGGLSAVDAFEIHVHRRPQGDKAPARFKAKLTGDPAAVTNDIHKKIALVKKLAFAFGDRNCSTITLQNITRGSIVVEWTNNTLPLEPCPKEQITALSRRIA
Source in vitro E.coli expression system
Gene Names DAG1
Protein Names Recommended name: Dystroglycan Alternative name(s): Dystrophin-associated glycoprotein 1 Cleaved into the following 2 chains: 1. Alpha-dystroglycan Short name= 2. Alpha-DG 3. Beta-dystroglycan Short name= 4. Beta-DG
Expression Region 30-653
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
Subcellular Location Alpha-dystroglycan: Secreted, extracellular space, SUBCELLULAR LOCATION: Beta-dystroglycan: Cell membrane, Single-pass type I membrane protein, Cytoplasm, cytoskeleton, Nucleus, nucleoplasm, Cell membrane, sarcolemma, Cell junction, synapse, postsynaptic cell membrane
Tissue Specificity Expressed in the myelin sheath of peripheral nerves.
Database Links

KEGG: bta:281439

STRING: 9913.ENSBTAP00000015385

UniGene: Bt.88492

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