Recombinant Chicken Beta-1,3-N-acetylglucosaminyltransferase radical fringe(RFNG)

Code CSB-CF019596CH
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O12972
Storage Buffer Tris-based buffer,50% glycerol
Species Gallus gallus (Chicken)
Sequence MNSSCLGLRRTCFLLSVTAAAVLLLLLPRGQPPAAPRRRPPPAGPSRPSPKREARPAGSDVPGDRGGGSGAAGGGRGVAGSPWPSRRVRMGPPGGSAKESLELKDIFIAVKTTRKYHKTRLELLFQTWISRARGQTFIFTDWEDRELRLKAGDHMINTNCSAVHTRQALCCKMSVEYDKFLESGQKWFCHVDDDNYVNPRTLLRLLSAFSPSQDVYVGRPSLDHPIEAADHVQSDGSKTSVKFWFATGGAGFCISRGLALKMSPWASLGNFISTAERVRLPDDCTIGYIIEGLLEVKLLHSPLFHSHLENLQRLQGESVLQQVTLSYGDPENKHNVVSVGGVFGLQQDPTRFKSVHCLLYPDTIWCPNKKMS
Source in vitro E.coli expression system
Gene Names RFNG
Protein Names Recommended name: Beta-1,3-N-acetylglucosaminyltransferase radical fringe EC= 2.4.1.222 Alternative name(s): O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Expression Region 1-372
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (By similarity). Plays an important role in limb outgrowth, it directs the formation and positioning of the apical ectodermal ridge (AER), one of the key organizer centers of vertebrate limb development
Subcellular Location Golgi apparatus membrane, Single-pass type II membrane protein
Protein Families Glycosyltransferase 31 family
Database Links

KEGG: gga:395789

STRING: 9031.ENSGALP00000004473

UniGene: Gga.4783

Pathway Notch signaling pathway

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