Insulin receptor-related protein
Short name= IRR
Cleaved into the following 2 chains:
1. Insulin receptor-related protein alpha chain
2. Insulin receptor-related protein
Full Length of Mature Protein
Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB (By similarity).
Membrane, Single-pass type I membrane protein
Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily