Recombinant Guinea pig Insulin receptor-related protein(INSRR)

Code CSB-CF011755GU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P14617
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Cavia porcellus (Guinea pig)
Sequence MNVCPSLDIRSEVAELRRLENCSVVEGHLQILLMFTATGEDFRSLSFPHLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGAHLFLGYALVIFEMPHLRDVGLPALGAVLHGSVRVEKNQELCHLSTIDWGLLQPTPSTNYIVGNKLGEECADVCPGTLGAAGEPCARTTFNGHTDYRCWTSSHCQRVCPCPQGLACTISGECCHTECLGGCSQPEDPRACVACRHFYYQSACHRACPLGTYEHESWRCVTAESCANLRSVPGRASTFGIHQGKCLAQCPPGFTRNGSSIFCHKCEGLCPKECKVGTKTIDSVQAAQDLVGCTHVEGSLILNLRRGYNLEPELQRSLGLVETITGFLKIKHSFALVSLSFFKNLKLIRGDTMVDGNYTLYVLDNQNLQQLGPWVSAGLTIPVGKIYFAFNPRLCLEHIYRLEEVTGTRGRQNKAEINPRTNGDRAACQTRTLRFVSNVTEADRILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGSQSWNLLDVELPLSRTQEPGVILAPLKPWTQYAVFVRAITLTTAEDSPHQGAQSPIVYLWTLPAAPTVPQDVISSSNSSSHLLVRWKPPTQRNGNITYYLVLWQRLAEDGDLYLNDYCHRGLRLPTSNHDPRFDREDGDLEAELELGCCPCQHAPPGQVLPALEAQEASFQKKFENFLHNAITIPKPPWKVTSIHRNLQRDAGRHRRAIGSPRPGGNSSDFEIQEDKVPRERA
Source in vitro E.coli expression system
Gene Names INSRR
Protein Names Recommended name: Insulin receptor-related protein Short name= IRR EC= 2.7.10.1 Alternative name(s): IR-related receptor Cleaved into the following 2 chains: 1. Insulin receptor-related protein alpha chain 2. Insulin receptor-related protein
Expression Region 27-746
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB (By similarity).
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily
Database Links

STRING: 10141.ENSCPOP00000017876

Pathway Regulation of actin cytoskeleton

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