Recombinant Human Ceramide synthase 1(CERS1)

Code CSB-CF012761HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P27544
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names CERS1
Protein Names Recommended name: Ceramide synthase 1 Short name= CerS1 Alternative name(s): LAG1 longevity assurance homolog 1 Longevity assurance gene 1 protein homolog 1 Protein UOG-1
Expression Region 1-350
Tag Info N-terminal 10xHis-tagged
Protein Description Full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner (By similarity).
Involvement in disease Epilepsy, progressive myoclonic 8 (EPM8)
Subcellular Location Endoplasmic reticulum membrane, Multi-pass membrane protein, SUBCELLULAR LOCATION: Isoform 1: Endoplasmic reticulum membrane, Multi-pass membrane protein, Golgi apparatus membrane, Multi-pass membrane protein
Database Links

HGNC: 14253

OMIM: 606919

KEGG: hsa:10715

STRING: 9606.ENSP00000402697

UniGene: Hs.412355

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