Recombinant Human EGF-like module-containing mucin-like hormone receptor-like 3(EMR3)

Code CSB-CF861168HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. Q9BY15
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names ADGRE3
Protein Names Recommended name: EGF-like module-containing mucin-like hormone receptor-like 3 Alternative name(s): EGF-like module receptor 3 Cleaved into the following 2 chains: 1. EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha
Expression Region 339-652
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of monocytes-derived macrophages and activated neutrophils.
Subcellular Location Cell membrane, Multi-pass membrane protein, SUBCELLULAR LOCATION: Isoform 3: Secreted
Protein Families G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Tissue Specificity Displays a predominantly leukocyte-restricted expression, with highest levels in neutrophils, monocytes and macrophages.
Database Links

HGNC: 23647

OMIM: 606101

KEGG: hsa:84658

STRING: 9606.ENSP00000253673

UniGene: Hs.658712

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