Recombinant Human Endothelin-converting enzyme 1(ECE1)

Code CSB-CF007371HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P42892
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names ECE1
Protein Names Recommended name: Endothelin-converting enzyme 1 Short name= ECE-1 EC=
Expression Region 1-770
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Converts big endothelin-1 to endothelin-1.
Involvement in disease Hirschsprung disease, cardiac defects, and autonomic dysfunction (HCAD)
Subcellular Location Cell membrane, Single-pass type II membrane protein
Protein Families Peptidase M13 family
Tissue Specificity All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A an
Database Links

HGNC: 3146

OMIM: 600423

KEGG: hsa:1889

STRING: 9606.ENSP00000364028

UniGene: Hs.195080

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