Recombinant Human Ephrin-B1(EFNB1)

Code CSB-CF007465HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P98172
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names EFNB1
Protein Names Recommended name: Ephrin-B1 Alternative name(s): EFL-3 ELK ligand Short name= ELK-L EPH-related receptor tyrosine kinase ligand 2 Short name= LERK-2
Expression Region 28-346
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).
Involvement in disease Craniofrontonasal syndrome (CFNS)
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Ephrin family
Tissue Specificity Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas.
Database Links

HGNC: 3226

OMIM: 300035

KEGG: hsa:1947

STRING: 9606.ENSP00000204961

UniGene: Hs.144700

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