Recombinant Human Epoxide hydrolase 1(EPHX1)

Code CSB-CF007734HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P07099
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Source in vitro E.coli expression system
Gene Names EPHX1
Protein Names Recommended name: Epoxide hydrolase 1 EC= Alternative name(s): Epoxide hydratase Microsomal epoxide hydrolase
Expression Region 1-455
Tag Info 10xHis-SUMO-tag
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water (By similarity). May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids
Involvement in disease Familial hypercholanemia (FHCA)
Subcellular Location Microsome membrane, Single-pass type III membrane protein, Endoplasmic reticulum membrane, Single-pass type III membrane protein
Protein Families Peptidase S33 family
Tissue Specificity Found in liver.
Database Links

HGNC: 3401

OMIM: 132810

KEGG: hsa:2052

STRING: 9606.ENSP00000272167

UniGene: Hs.89649

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