Recombinant Human Epsilon-sarcoglycan(SGCE)

Code CSB-CF021185HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O43556
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MQLPRWWELGDPCAWTGQGRGTRRMSPATTGTFLLTVYSIFSKVHSDRNVYPSAGVLFVHVLEREYFKGEFPPYPKPGEISNDPITFNTNLMGYPDRPGWLRYIQRTPYSDGVLYGSPTAENVGKPTIIEITAYNRRTFETARHNLIINIMSAEDFPLPYQAEFFIKNMNVEEMLASEVLGDFLGAVKNVWQPERLNAINITSALDRGGRVPLPINDLKEGVYVMVGADVPFSSCLREVENPQNQLRCSQEMEPVITCDKKFRTQFYIDWCKISLVDKTKQVSTYQEVIRGEGILPDGGEYKPPSDSLKSRDYYTDFLITLAVPSAVALVLFLILAYIMCCRREGVEKRNMQTPDIQLVHHSAIQKSTKELRDMSKNREIAWPLSTLPVFHPVTGEIIPPLHTDNYDSTNMPLMQTQQNLPHQTQIPQQQTTGKWYP
Source in vitro E.coli expression system
Gene Names SGCE
Protein Names Recommended name: Epsilon-sarcoglycan Short name= Epsilon-SG
Expression Region 1-437
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Involvement in disease Dystonia 11, myoclonic (DYT11)
Subcellular Location Cell membrane, sarcolemma, Single-pass membrane protein, Cytoplasm, cytoskeleton, Cell projection, dendrite, Golgi apparatus
Protein Families Sarcoglycan alpha/epsilon family
Tissue Specificity Ubiquitous.
Database Links

HGNC: 10808

OMIM: 159900

KEGG: hsa:8910

UniGene: Hs.371199

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