Recombinant Human Killer cell immunoglobulin-like receptor 2DS4(KIR2DS4)

Code CSB-CF012362HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P43632
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Sequence QEGVHRKPSFLALPGHLVKSEETVILQCWSDVMFEHFLLHREGKFNNTLHLIGEHHDGVSKANFSIGPMMPVLAGTYRCYGSVPHSPYQLSAPSDPLDMVIIGLYEKPSLSAQPGPTVQAGENVTLSCSSRSSYDMYHLSREGEAHERRLPAVRSINGTFQADFPLGPATHGGTYRCFGSFRDAPYEWSNSSDPLLVSVTGNPSNSWPSPTEPSSKTGNPRHLHVLIGTSVVKIPFTILLFFLLHRWCSDKKNAAVMDQEPAGNRTVNSEDSDEQDHQEVSYA
Source in vitro E.coli expression system
Gene Names KIR2DS4
Protein Names Recommended name: Killer cell immunoglobulin-like receptor 2DS4 Alternative name(s): CD158 antigen-like family member I MHC class I NK cell receptor Natural killer-associated transcript 8 Short name= NKAT-8 P58 natural killer cell receptor cl
Expression Region 22-304
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
Subcellular Location Cell membrane, Single-pass type I membrane protein
Protein Families Immunoglobulin superfamily
Database Links

HGNC: 6336

OMIM: 604955

KEGG: hsa:3809

UniGene: Hs.654608

Pathway Antigen processing and presentation
Natural killer cell mediated cytotoxicity

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