Recombinant Human Synaptotagmin-5(SYT5)

Code CSB-CF023041HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O00445
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP
Source in vitro E.coli expression system
Gene Names SYT5
Protein Names Recommended name: Synaptotagmin-5 Alternative name(s): Synaptotagmin V Short name= SytV
Expression Region 1-386
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity).
Subcellular Location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Single-pass membrane protein, Recycling endosome membrane, Single-pass membrane protein
Protein Families Synaptotagmin family
Database Links

HGNC: 11513

OMIM: 600782

KEGG: hsa:6861

STRING: 9606.ENSP00000346265

UniGene: Hs.631566

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