Recombinant Lymnaea stagnalis Octopamine receptor 2

Code CSB-CF515313LRQ
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O01670
Storage Buffer Tris-based buffer,50% glycerol
Species Lymnaea stagnalis (Great pond snail) (Helix stagnalis)
Sequence MMSFPIALFADVNQSFRANLVVSSYHHAITFPTVRGANFSTFFPRNFSVSADVWLCGANF SQEWQLMQPVCSTKYDSITIFITVAVVLTLITLWTILGNFFVLMALYRYGTLRTMSNCLI GNLAISDLLLAVTVLPISTVHDLLGYWVFGEFTCTLWLCMDVLYCTASIWGLCTVAFDRY LATVYPVWYHDQRSVRKAVGCIVFVWIFSIVISFAPFIGWQHMIPSFFSFNASIQRYQCI LFTSSSYVLYSSMGSFVIPAILMAFMYVRIFVVLHNQSRGVKFKSGLKISSSKYNGCPVI NEPSREGINGLGRDVTNTTLLSDAVGSSADLTSNGKDDPRVLATAPIELTEDVPPLNGHH HRTVHETPYVSGLHTKRSNSFALPTELEKKCKPLTNNILHMMDFDRRNSHNAVIQRSASE MVNLDVSKHELLISNVCHRSKSATALTSETGDPLGSLAGPRRSLQCNVGGLVRNKHMTLS MKRRFELREQRATKRMLLIMACFCVCWMPFLFMYILRSVCDTCHMNQHFVAAIIWLGYVN SSLNPVLYTLFNDDFKVAFKRLIGARSPSAYRSPGPRR
Source in vitro E.coli expression system
Protein Names Recommended name: Octopamine receptor 2 Short name= OA2
Expression Region 1-578
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Receptor for octopamine. Octopamine (OA) is a neurotransmitter, neurohormone, and neuromodulator in invertebrates. This receptor induces a long lasting opening of voltage- independent chloride channels, a process which seems to involve protein phosphorylation but does not require either cAPK or PKC. The rank order of potency for agonists is p-synephrine > p-octopamine > xylometazoline > B-HT920 > norepinephrine = clonidine > epinephrine > p-tyramine > phenylephrine = oxymetazoline = mehoxamine = dopamine > serotonin > histamine. For antagonists, the rank order is rauwolscine = mianserin > phentolamine > chlorpromazine > spiperone > yohimbine > propanolol > alprenolol > prazosine > pindolol.
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families G-protein coupled receptor 1 family

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