Recombinant Macaca mulatta (Rhesus macaque) fMet-Leu-Phe receptor(FPR1)

Code CSB-CF008854MOW
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P79189
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Macaca mulatta (Rhesus macaque)
Sequence NSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMRHTVTTIS YLNLAVADFCFTSTLPFLMVVKVMRGHWPFGWFLCKFIFTIVDINLFGSVFLIALIALDR CVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFDFSPW TNDPVEKLKVTIAMLTVRGIIRFIIGFSVPMSIVAVSYGLIATKIHKQGLIKSSRPLRVL SFVVAAFFLCWSPYQVVAFIATVRLRNILQGLSKELRIAVDATSALAFFNSCLNPMLYVF MGQDFRERLIHSLPTSLERALTEDSAQTSDTATNSTLPSAEVPLQA
Source in vitro E.coli expression system
Gene Names FPR1
Protein Names Recommended name: fMet-Leu-Phe receptor Short name= fMLP receptor Alternative name(s): N-formyl peptide receptor Short name= FPR N-formylpeptide chemoattractant receptor
Expression Region 1-346
Tag Info N-terminal 10xHis-tagged
Protein Description Full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families G-protein coupled receptor 1 family
Database Links

STRING: 9544.ENSMMUP00000017142

UniGene: Mmu.25424

Pathway Rap1 signaling pathway

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