Recombinant Mouse Calmegin(Clgn)

Code CSB-CF005544MO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P52194
Storage Buffer Tris-based buffer,50% glycerol
Species Mus musculus (Mouse)
Sequence DFMDDGVEVEDFSENSDESNIKDEPSSGTFKYKTPQPIGEVYFTETFDSGNLAGWVLSKAKKDDMDSEIAIYDGRWEIEELKENQVPGDRGLVLKSKAKHHAIAAVLEKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTGDLILENFYDKTSYTIMFGPDKCGEDYKLHLIFRHKHPKTGVFEEKHAKPPDVDLKEFFTDRKTHLYTLVMNPDDTFEVLIDQKVVNQGTLLDDVVPPINPPREIDDPSDKKPEEWDDRAKIPDPTAVRPEDWDENEPAQIEDSSAVKPDGWLDDEPKFIPNPKAEKPEDWSDDMDGEWEAPHIPNPACQIGCGEWKPPMIDNPKYKGIWRPPMINNPNYQGLWSPQKIPNPDYFEDDHPFLLTSFSALGLELWSMTPDIYFDNFIICSEKEVADQWATDGWELKIMVANANEPGVLRQLVIAAEERPWLWLMYLVMAGLPVALVASFCWPRKVKKKYEDTGPKKTELCKLQSKAALEQEAEEEKAPEKPEDVQEEKKPGEAEVVTVEKEVIGEPEEKSKEDRETLEGQEEVSKLSKSGSEDEMKDADESPGSGDAPLKSLRKRRVRKD
Source in vitro E.coli expression system
Gene Names Clgn
Protein Names Recommended name: Calmegin Alternative name(s): A2/6 Calnexin-T MEG 1 antigen
Expression Region 20-611
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions.
Subcellular Location Endoplasmic reticulum membrane, Single-pass type I membrane protein
Protein Families Calreticulin family
Tissue Specificity Detected in testis (at protein level). Detected in testis.
Database Links

KEGG: mmu:12745

STRING: 10090.ENSMUSP00000002259

UniGene: Mm.358581

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