Recombinant Mouse Desmocollin-3(Dsc3)

Code CSB-CF007191MO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P55850
Storage Buffer Tris-based buffer,50% glycerol
Species Mus musculus (Mouse)
Source in vitro E.coli expression system
Gene Names Dsc3
Protein Names Recommended name: Desmocollin-3
Expression Region 136-896
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Subcellular Location Cell membrane, Single-pass type I membrane protein, Cell junction, desmosome
Tissue Specificity First expressed at E13.0 in epithelium of whisker pads and external nares, and in most mature vibrissa follicles. 12 hours later, prominently expressed in whiskers and tactile follicles above the eye. At E14.5, also expressed in developing nails and teeth
Database Links

KEGG: mmu:13507

STRING: 10090.ENSMUSP00000111514

UniGene: Mm.89935

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