Recombinant Mouse Polypeptide N-acetylgalactosaminyltransferase 3(Galnt3)

Code CSB-CF009210MO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P70419
Storage Buffer Tris-based buffer,50% glycerol
Species Mus musculus (Mouse)
Sequence MAHLKRLVKLHIKRHYHRKFWKLGAVIFFFLVVLILMQREVSVQYSKEESKMERNLKNKNKMLDFMLEAVNNIKDAMPKMQIGAPIKENIDVRERPCLQGYYTAAELKPVFDRPPQDSNAPGASGKPFKITHLSPEEQKEKERGETKHCFNAFASDRISLHRDLGPDTRPPECIEQKFKRCPPLPTTSVIIVFHNEAWSTLLRTVHSVLYSSPAILLKEIILVDDASVDDYLHEKLEEYIKQFSIVKIVRQQERKGLITARLLGAAVATAETLTFLDAHCECFYGWLEPLLARIAENYTAVVSPDIASIDLNTFEFNKPSPYGSNHNRGNFDWSLSFGWESLPDHEKQRRKDETYPIKTPTFAGGLFSISKKYFEHIGSYDEEMEIWGGENIEMSFRVWQCGGQLEIMPCSVVGHVFRSKSPHTFPKGTQVIARNQVRLAEVWMDEYKEIFYRRNTDAAKIVKQKSFGDLSKRFEIKKRLQCKNFTWYLNTIYPEAYVPDLNPVISGYIKSVGQPLCLDVGENNQGGKPLILYTCHGLGGNQYFEYSAQREIRHNIQKELCLHATQGVVQLKACVYKGHRTIAPGEQIWEIRKDQLLYNPLFKMCLSSNGEHPNLVPCDATDLLQKWIFSQND
Source in vitro E.coli expression system
Gene Names Galnt3
Protein Names Recommended name: Polypeptide N-acetylgalactosaminyltransferase 3 EC= 2.4.1.41 Alternative name(s): Polypeptide GalNAc transferase 3 Short name= GalNAc-T3 Short name= pp-GaNTase 3 Protein-UDP acetylgalactosaminyltransferase 3 UDP-GalNAc:p
Expression Region 1-633
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Glycosylates FGF23 (By similarity). Probably glycosylates fibronectin in vivo. May be involved in phosphate homeostasis.
Subcellular Location Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein
Protein Families Glycosyltransferase 2 family, GalNAc-T subfamily
Tissue Specificity Highly expressed in the reproductive tract, principally in the testis and uterus, and to a lesser degree in the cervix with only trace levels in the ovary. Also expressed at high level in sublingual gland, stomach and colon, with more moderate amounts pre
Database Links

KEGG: mmu:14425

STRING: 10090.ENSMUSP00000028378

UniGene: Mm.439760

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