Recombinant Mouse Probable G-protein coupled receptor 83 (Gpr83)

Code CSB-CF009835MO
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names
Uniprot No.
Alternative Names
Gpr83; Gir; Gpr72; Probable G-protein coupled receptor 83; Glucocorticoid-induced receptor
Mus musculus (Mouse)
Expression Region
Target Protein Sequence
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Please contact us to get it.

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Target Background

Orphan receptor. Could be a neuropeptide Y receptor.
Gene References into Functions
  1. this study identified a receptor for PEN in mouse hypothalamus and Neuro2A cellsit. It is GPR83. PMID: 27117253
  2. Data indicate that the extracellular portion of G-protein coupled receptor 83 (GPR83) has a strong regulatory function on this receptor. PMID: 25516095
  3. Gpr83 modulates ghrelin action and Gpr83 regulates systemic metabolism through other ghrelin-independent pathways. PMID: 23744028
  4. GIR -/- mice show increased preference for sucrose, delayed acquisition of spatial learning and insensitivity to the anxiogenic effects of restraint stress. PMID: 23088626
  5. GPR83 may participate in central thermoregulation and the central control of circulating adiponectin. PMID: 22560055
  6. Gpr83 is critically involved in the peripheral conversion of Foxp3-negative to Foxp3-expressing regulatory T cells in vivo. PMID: 16785516
  7. These results demonstrate that GPR83 is dispensable for Treg-cell development and function. PMID: 17893329

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Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family
Tissue Specificity
Brain, thymus and spleen.
Database Links
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