Recombinant Pig Glutamate carboxypeptidase 2(FOLH1)

Code CSB-CF008782PI
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O77564
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Sus scrofa (Pig)
Source in vitro E.coli expression system
Gene Names FOLH1
Protein Names Recommended name: Glutamate carboxypeptidase 2 EC= Alternative name(s): Folate hydrolase 1 Folylpoly-gamma-glutamate carboxypeptidase Short name= FGCP Glutamate carboxypeptidase II Short name= GCPII Membrane glutamate carboxyp
Expression Region 1-751
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides (By similarity). In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate.
Subcellular Location Cell membrane, Single-pass type II membrane protein
Protein Families Peptidase M28 family, M28B subfamily
Tissue Specificity High expression in the duodenum and in the jejunum brush-border membrane. Weak expression in kidney.
Database Links

KEGG: ssc:397677

STRING: 9823.ENSSSCP00000027466

UniGene: Ssc.14488

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