Recombinant Rabbit Chloride intracellular channel protein 6 (CLIC6)

Code CSB-CF878796RB
MSDS
Size Pls inquire
Source in vitro E.coli expression system
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Product Details

Target Names
CLIC6
Uniprot No.
Alternative Names
CLIC6; Chloride intracellular channel protein 6; Parchorin
Species
Oryctolagus cuniculus (Rabbit)
Expression Region
1-637
Target Protein Sequence
MAETAEPEGGAPSPQGPPEGSALLEERPGEPDPAGPEASEGAAKAPSGEGAGAAAKAGAT EEASGGRDGEGAGEQAPDAGTESGGETPDAKGAQIEAEGAPEGTKAPQLGEEGSGGKQVE ESGPDCELRGEAAREAEGQAAAPAAPGAQEEAVPGDSVDAEGSIDAGGSVDAAGSVDAGG SIDAGGSMDAGGSVDAGGSIDTGGSVDAAGSVDAGGSIDTGRNVDAGGSIDAGGSVDAGG SMDAEGPAGGAHGAGGEPQDLGAGSPQPRSEAVEVAAAENEGHSPGESVEDAAAEEAAGT REPEGSEDAAGEDGDQGRPQEETEQQAERQEPGPETQSEEEERPPDRSPDGEAAASTRAA QPEAELSNHLAAEEGGQRGEGPANGRGEDGEASEEGDPGQEHDITLFVKAGYDGESIGNC PFSQRLFMILWLKGVIFNVTTVDLKRKPADLQNLAPGTNPPFMTFDGDVKTDVNKIEEFL EEKLAPPRYPKLATQHPESNSAGNDVFAKFSAFIKNTKKDANEIYEKSLLKALKKLDAYL NSPLPDEVDAYSTEDVAVSGRKFLDGDDLTLADCNLLPKLHIIKIVAKKYRDFEFPPEMT GIWRYLNNAYARDEFINTCPADQEIEHAYSDVAKRMK
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport.
Subcellular Location
Cytoplasm. Cell membrane; Single-pass membrane protein. Note=Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane.
Protein Families
Chloride channel CLIC family
Tissue Specificity
Expressed in brain, chorioretinal, lacrimal glands, submandibular glands, airway epithelium, kidney and gastric mucosa, where it is preferentially expressed in cells that secrete or transport water. In brain, it is highly expressed in choroid plexus. Not
Database Links

KEGG: ocu:100008620

UniGene: Ocu.2437

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