Recombinant Rat Gastrin-releasing peptide receptor(Grpr)

Code CSB-CF009943RA
Size Pls inquire other sizes
Source in vitro E.coli expression system
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Product Details

Target Names Grpr
Uniprot No. P52500
Alternative Names GrprGastrin-releasing peptide receptor; GRP-R; GRP-preferring bombesin receptor
Species Rattus norvegicus (Rat)
Expression Region 1-384
Protein Length Full length protein
Tag Info The following tags are available.
N-terminal 10xHis-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

Target Data

Function Receptor for gastrin-releasing peptide (GRP)
Gene References into Functions
  1. peptidergic pathways comprise the core of a sigh control circuit that integrates physiological and perhaps emotional input to transform normal breaths into sighs PMID: 26855425
  2. These findings highlight the role of GRPR signaling in sepsis outcome. PMID: 22735756
  3. activation in the lumbosacral spinal cord required for ejaculation PMID: 22429708
  4. The mRNA for the major receptor subtype, GRP-R, was present in fetal and adult rat kidneys PMID: 15140764
  5. Data suggest that the memory-impairing effects of gastrin-releasing peptide receptor antagonists might be mediated by inhibition of function and/or expression of neuronal bFGF or diminished bFGF signaling. PMID: 17406984

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Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families G-protein coupled receptor 1 family
Database Links

KEGG: rno:24938

STRING: 10116.ENSRNOP00000005559

UniGene: Rn.10316

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